Vitaran: Polynucleotide Skin Booster — Istanbul
Vitaran is a polynucleotide (PN) skin booster made by BR Pharm in South Korea from purified trout DNA. It is used to improve fine lines, elasticity and skin quality, not to add volume. Veneta in Nişantaşı offers Vitaran after a skin assessment by a physician.
Last updated: October 2026
At a Glance
Type
Polynucleotide (PN) skin booster; medical device
Manufacturer
BR Pharm, South Korea
Sessions
Usually 3–4, about 3–4 weeks apart
Results last
No manufacturer figure; maintenance every 4–9 months in UK sources
Downtime
Redness and small bumps for 1–2 days
What Is Vitaran?
Vitaran contains 20 mg/ml of polynucleotides (PN): long DNA fragments purified from sea trout raised on land-based farms in South Korea. BR Pharm sells it as HP Vitaran, and LG Chem markets it in Korea as Vitaran.
In Korea it is an approved medical device: in a randomised trial, its eye formula proved non-inferior to a comparison product for crow’s feet. It also carries the CE mark.
Vitaran Products
| Product | What it is | Typical use |
|---|---|---|
| Vitaran | PN 20 mg/ml, medium viscosity | Skin quality and fine lines on the face |
| Vitaran i | PN 20 mg/ml, low viscosity | Thin skin around the eyes, including crow’s feet |
| Vitaran S | PN 20 mg/ml, high viscosity | Scars and uneven texture |
In the UK, Vitaran I and Vitaran II are the same 2% formula in 1 ml and 2 ml syringes.
Who Vitaran Suits
- Fine lines and loss of elasticity, when quality matters more than volume.
- Crow’s feet and thin skin around the eyes, where Vitaran i was studied.
- Dull skin on the face, neck, décolletage or hands.
- Scars and uneven texture, with Vitaran S.
- Not suitable in pregnancy or breastfeeding, or with an active skin infection or fish allergy; blood thinners and autoimmune conditions need a physician’s review.
How the Treatment Works at Veneta
Skin assessment
A physician examines your skin, asks about allergies (including fish) and medicines, and chooses Vitaran, Vitaran i or Vitaran S.
Preparation
The skin is cleansed and disinfected; a numbing cream can be applied.
Micro-injections
Small deposits of gel are injected into the dermis with a very fine needle.
Aftercare and follow-up
Redness and small bumps usually fade within 24–48 hours; small bruises can occur. Avoid saunas, intense exercise and strong sun for a day or two. Next session: about 3–4 weeks later.
Skin Boosters: Average Prices in Istanbul
Average Istanbul market prices compiled in October 2026, for orientation. The price of a specific product is confirmed after your consultation.
| Treatment | Unit | Average price | Typical range |
|---|---|---|---|
| Classic medical facial | per session | 3,000 TRY≈ €55 | 2,000–5,000 TRY≈ €35–€90 |
| Chemical peel (superficial to medium) | per session | 4,000 TRY≈ €70 | 2,500–7,500 TRY≈ €45–€135 |
| Carbon laser peel | per session | 2,500 TRY≈ €45 | 1,500–5,000 TRY≈ €25–€90 |
| Skin booster (injectable hyaluronic acid) | per session, face | 15,000 TRY≈ €270 | 10,000–25,000 TRY≈ €180–€450 |
| Profhilo | per session, 2 ml | 20,000 TRY≈ €360 | 15,000–25,000 TRY≈ €270–€450 |
| Salmon DNA / polynucleotides (PDRN) | per session | 6,000 TRY≈ €105 | 2,500–11,500 TRY≈ €45–€205 |
| Facial mesotherapy | per session | 5,000 TRY≈ €90 | 3,000–9,000 TRY≈ €55–€160 |
| PRP for the face | per session | 8,000 TRY≈ €145 | 5,000–12,000 TRY≈ €90–€215 |
| Exosome treatment — face | per session | 15,000 TRY≈ €270 | 10,000–25,000 TRY≈ €180–€450 |
| IPL (Lumecca) — face | per session | 10,000 TRY≈ €180 | 5,000–15,000 TRY≈ €90–€270 |
| Dermapen microneedling | per session, face | 7,000 TRY≈ €125 | 5,000–10,000 TRY≈ €90–€180 |
| Morpheus8 — face | per session | 26,000 TRY≈ €465 | 20,000–35,000 TRY≈ €360–€625 |
| HIFU — full face | per session | 25,000 TRY≈ €450 | 15,000–35,000 TRY≈ €270–€625 |
| Fractional CO2 laser — full face | per session | 25,000 TRY≈ €450 | 5,000–60,000 TRY≈ €90–€1,075 |
| Stretch mark treatment — one area | per session | 15,000 TRY≈ €270 | 7,500–35,000 TRY≈ €135–€625 |
Average Istanbul prices compiled in October 2026, for orientation only. Your personal price depends on the product, the amount and the plan agreed at your consultation. Euro amounts are approximate, converted at 55.86 TRY = 1 EUR.
Vitaran Compared With Other Skin Boosters
Vitaran, Rejuran, Plinest and Nucleofill are all polynucleotide boosters; they differ in manufacturer, fish source, concentration and range. Rejuran is also Korean but uses salmon DNA; Plinest is Italian.
Vitaran is a PN product, not PDRN: PDRN consists of shorter, lower-molecular-weight DNA fragments. See the polynucleotide overview.
Related treatments
Frequently Asked Questions
What is Vitaran?
How many Vitaran sessions do I need?
How long does Vitaran last?
Is there downtime after Vitaran?
Is Vitaran PDRN?
This page is general information and does not replace a medical consultation. Whether Vitaran suits you is decided by our physicians after a skin assessment.
Free Consultation — Vitaran in Istanbul
Send us a WhatsApp message or book a video call; the consultation is free. You receive a written plan with the product, number of sessions and price before treatment.
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