SKIN BOOSTER · REJURAN

Rejuran: Salmon DNA Skin Booster — Istanbul

Rejuran is a polynucleotide (PN) skin booster made by PharmaResearch in South Korea from purified salmon DNA. It is used to improve skin texture, elasticity and fine lines, not to add volume. Veneta in Nişantaşı offers Rejuran after a skin assessment by a physician.

Last updated: October 2026

At a Glance

Type

Polynucleotide (PN) skin booster

Manufacturer

PharmaResearch, South Korea

Sessions

Usually 3–4, 2–4 weeks apart (clinic sources)

Results last

No manufacturer figure; maintenance every 6–12 months is commonly planned

Downtime

Small bumps for about a day

What Is Rejuran?

Rejuran is a range of injectable skin boosters based on polynucleotides (PN): long DNA fragments purified from salmon with PharmaResearch’s patented DOT (DNA Optimizing Technology) process. The original product, often called Rejuran Healer, contains 20 mg/ml of PN.

In the dermis, PN are thought to support the skin’s own repair and hydration, so results build over a course. Rejuran is a registered medical device in South Korea and a Class III medical device in Australia.

Rejuran Products

Product	What it is	Typical use
Rejuran (Rejuran Healer)	Original PN formula, 20 mg/ml	Texture and fine lines across the face
Rejuran i	PN formula for thin skin	The eye area
Rejuran S	More viscous PN formula	Depressed acne scars and wrinkles
Rejuran HB Plus	PN with hyaluronic acid and lidocaine	Same uses, with lidocaine for less pain

Who Rejuran Suits

Dull, thin or tired-looking skin that needs better quality rather than volume.
Fine lines on the face and around the eyes.
Depressed (atrophic) acne scars, treated with Rejuran S.
Not suitable in pregnancy or breastfeeding, or with a skin infection or fish allergy; blood thinners and autoimmune conditions need a physician’s review.

How the Treatment Works at Veneta

Skin assessment

A physician examines your skin, asks about allergies (including fish) and medicines, and chooses the Rejuran product.

Numbing

The skin is cleansed and a numbing cream is applied; Rejuran HB Plus also contains lidocaine.

Micro-injections

Many small deposits are placed in the dermis with a fine needle, or into the base of depressed scars.

Aftercare and follow-up

Small bumps fade within about a day; redness or a small bruise may last a few days. Next session: 2–4 weeks later.

Skin Boosters: Average Prices in Istanbul

Average Istanbul market prices compiled in October 2026, for orientation. The price of a specific product is confirmed after your consultation.

Treatment	Unit	Average price	Typical range
Classic medical facial	per session	3,000 TRY≈ €55	2,000–5,000 TRY≈ €35–€90
Chemical peel (superficial to medium)	per session	4,000 TRY≈ €70	2,500–7,500 TRY≈ €45–€135
Carbon laser peel	per session	2,500 TRY≈ €45	1,500–5,000 TRY≈ €25–€90
Skin booster (injectable hyaluronic acid)	per session, face	15,000 TRY≈ €270	10,000–25,000 TRY≈ €180–€450
Profhilo	per session, 2 ml	20,000 TRY≈ €360	15,000–25,000 TRY≈ €270–€450
Salmon DNA / polynucleotides (PDRN)	per session	6,000 TRY≈ €105	2,500–11,500 TRY≈ €45–€205
Facial mesotherapy	per session	5,000 TRY≈ €90	3,000–9,000 TRY≈ €55–€160
PRP for the face	per session	8,000 TRY≈ €145	5,000–12,000 TRY≈ €90–€215
Exosome treatment — face	per session	15,000 TRY≈ €270	10,000–25,000 TRY≈ €180–€450
IPL (Lumecca) — face	per session	10,000 TRY≈ €180	5,000–15,000 TRY≈ €90–€270
Dermapen microneedling	per session, face	7,000 TRY≈ €125	5,000–10,000 TRY≈ €90–€180
Morpheus8 — face	per session	26,000 TRY≈ €465	20,000–35,000 TRY≈ €360–€625
HIFU — full face	per session	25,000 TRY≈ €450	15,000–35,000 TRY≈ €270–€625
Fractional CO2 laser — full face	per session	25,000 TRY≈ €450	5,000–60,000 TRY≈ €90–€1,075
Stretch mark treatment — one area	per session	15,000 TRY≈ €270	7,500–35,000 TRY≈ €135–€625

Average Istanbul prices compiled in October 2026, for orientation only. Your personal price depends on the product, the amount and the plan agreed at your consultation. Euro amounts are approximate, converted at 55.86 TRY = 1 EUR.

Rejuran Compared With Other Skin Boosters

Rejuran, Plinest, Nucleofill and Vitaran all contain polynucleotides; they differ in manufacturer, fish source, concentration and product range. See the polynucleotide overview.

PN is not the same as PDRN: PDRN consists of shorter, lower-molecular-weight DNA fragments, while PN chains are longer and form a gel in the skin. PharmaResearch makes both, but Rejuran is a PN product. See also salmon DNA and PDRN.

Related treatments

Frequently Asked Questions

What is Rejuran?

Rejuran is an injectable polynucleotide (PN) skin booster made by PharmaResearch in South Korea from purified salmon DNA. It is used to improve skin texture, elasticity and fine lines, not to add volume.

How many Rejuran sessions do I need?

PharmaResearch publishes no fixed protocol. Clinic and distributor sources describe 3–4 sessions 2–4 weeks apart, followed by maintenance every 6–12 months.

How long does Rejuran last?

Rejuran results build gradually over the course. PharmaResearch publishes no duration; clinic and distributor sources plan maintenance every 6–12 months.

Is there downtime after Rejuran?

Little. Small bumps fade within about a day, and redness or a small bruise within a few days; most people resume their routine within two to three days.

Is Rejuran the same as PDRN?

No. Rejuran contains polynucleotides (PN), which are longer DNA chains with a higher molecular weight than PDRN.

This page is general information and does not replace a medical consultation. Whether Rejuran suits you is decided by our physicians after a skin assessment.

Free Consultation — Rejuran in Istanbul

Send us a WhatsApp message or book a video call; the consultation is free. You receive a written plan with the product, number of sessions and price before treatment.

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