SKIN BOOSTER · PLURYAL

Pluryal: Skin Boosters and Polynucleotides — Istanbul

Pluryal® is a range of injectables from MD Skin Solutions, Luxembourg. For skin quality it offers Pluryal Booster, a hyaluronic acid (HA) booster, and the polynucleotide products Pluryal Densify and Pluryal Silk. At Veneta in Nişantaşı, Istanbul, our physicians offer Pluryal after a skin assessment.

Last updated: October 2026

At a Glance

Type

HA and polynucleotide (PN) skin boosters

Manufacturer

MD Skin Solutions, Luxembourg

Sessions

Densify: 3, three weeks apart

Results last

No fixed figure; regular maintenance sessions

Downtime

Usually little; small bumps or redness

What Is Pluryal?

MD Skin Solutions makes Pluryal in Luxembourg; the range spans polynucleotide “densifiers”, an HA skin booster and fillers, and its HA fillers are made with partner Croma-Pharma (Austria). Its Mesoline serums are used with microneedling, not injected.

Polynucleotides (PN) are purified DNA fragments. Pluryal Densify combines 10 mg/ml PN with 10 mg/ml non-cross-linked HA and 40 mg/ml mannitol, which protects the HA from breakdown; Pluryal Silk contains 7.5 mg/ml PN. Both are Class III medical devices.

Pluryal Products

Product	What it is	Typical use
Pluryal Booster	HA skin booster with glycerol	Hydration and fine lines; superficial dermis
Pluryal Densify	PN with non-cross-linked HA and mannitol	Dull, dehydrated skin of the face (not under the eyes), neck, décolletage, hands
Pluryal Silk	PN	Thin skin around the eyes and mouth; acne scars, stretch marks
Pluryal Classic, Volume, Contour Lidocaine	Cross-linked HA fillers	Wrinkles, folds and volume — not skin boosters

Who Pluryal Suits

Dull, dehydrated or tired skin on the face, neck, décolletage or hands (Densify, Booster).
Thin, delicate skin around the eyes and mouth (Silk).
Fine lines such as crow’s feet and smoker’s lines (Booster).
Not suitable with infection or inflammation in the area or an ingredient allergy; Densify starts three weeks after a laser, surgery or fillers.

How the Treatment Works at Veneta

Skin assessment

A physician assesses your skin and medical history and chooses Booster, Densify or Silk for each area.

Preparation

The skin is cleansed and disinfected; a numbing cream is optional.

Injection

Small droplets with a fine needle, or a cannula: Booster in the superficial dermis, Densify and Silk deeper.

Aftercare and follow-up

Small bumps or redness settle on their own. Densify follows the manufacturer’s course of three sessions three weeks apart, then maintenance.

Skin Boosters: Average Prices in Istanbul

Average Istanbul market prices compiled in October 2026, for orientation. The price of a specific product is confirmed after your consultation.

Treatment	Unit	Average price	Typical range
Classic medical facial	per session	3,000 TRY≈ €55	2,000–5,000 TRY≈ €35–€90
Chemical peel (superficial to medium)	per session	4,000 TRY≈ €70	2,500–7,500 TRY≈ €45–€135
Carbon laser peel	per session	2,500 TRY≈ €45	1,500–5,000 TRY≈ €25–€90
Skin booster (injectable hyaluronic acid)	per session, face	15,000 TRY≈ €270	10,000–25,000 TRY≈ €180–€450
Profhilo	per session, 2 ml	20,000 TRY≈ €360	15,000–25,000 TRY≈ €270–€450
Salmon DNA / polynucleotides (PDRN)	per session	6,000 TRY≈ €105	2,500–11,500 TRY≈ €45–€205
Facial mesotherapy	per session	5,000 TRY≈ €90	3,000–9,000 TRY≈ €55–€160
PRP for the face	per session	8,000 TRY≈ €145	5,000–12,000 TRY≈ €90–€215
Exosome treatment — face	per session	15,000 TRY≈ €270	10,000–25,000 TRY≈ €180–€450
IPL (Lumecca) — face	per session	10,000 TRY≈ €180	5,000–15,000 TRY≈ €90–€270
Dermapen microneedling	per session, face	7,000 TRY≈ €125	5,000–10,000 TRY≈ €90–€180
Morpheus8 — face	per session	26,000 TRY≈ €465	20,000–35,000 TRY≈ €360–€625
HIFU — full face	per session	25,000 TRY≈ €450	15,000–35,000 TRY≈ €270–€625
Fractional CO2 laser — full face	per session	25,000 TRY≈ €450	5,000–60,000 TRY≈ €90–€1,075
Stretch mark treatment — one area	per session	15,000 TRY≈ €270	7,500–35,000 TRY≈ €135–€625

Average Istanbul prices compiled in October 2026, for orientation only. Your personal price depends on the product, the amount and the plan agreed at your consultation. Euro amounts are approximate, converted at 55.86 TRY = 1 EUR.

Pluryal Compared With Other Skin Boosters

Pluryal Densify and Silk belong to the polynucleotide category, like Plinest, Rejuran or Nucleofill; see our polynucleotide page. Pluryal Booster is an HA booster; the main brands are compared on our skin booster brands page.

Related treatments

Frequently Asked Questions

What is Pluryal?

Pluryal is a range of injectables by MD Skin Solutions, Luxembourg. Its skin-quality products are Pluryal Booster (hyaluronic acid) and Pluryal Densify and Pluryal Silk (polynucleotides).

Is Pluryal a filler or a skin booster?

Both exist under the Pluryal name. Pluryal Booster, Densify and Silk are for skin quality, while Pluryal Classic, Volume and Contour Lidocaine are hyaluronic acid fillers.

How many Pluryal sessions do I need?

For Pluryal Densify, the manufacturer’s protocol is three sessions three weeks apart; for Pluryal Silk, three sessions three weeks apart for younger skin or four sessions two weeks apart for older skin.

How long does Pluryal last?

Pluryal has no fixed duration; product information advises maintenance every 2–3 months for Densify and every 1–3 months for Silk, and supplier data give every 4–6 months for Booster.

Is there downtime after Pluryal?

Usually little. Small bumps, redness or slight bruising at the injection points usually settle on their own.

This page is general information and does not replace a medical consultation. Whether Pluryal suits you is decided by our physicians after a skin assessment.

Free Consultation — Pluryal in Istanbul

Send us a WhatsApp message or book a video call; the consultation is free. You receive a written plan with the product, number of sessions and price before treatment.

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